The firm will begin construction on the bridge Ponte della Musica in April this year along with C Lotti and Associati (a Rome-based civil engineering firm) and Powell-Williams Architects.
The Ponte della Musica will consist of two incline steel arches supporting a steel deck, which can be converted from its initial pedestrianised form for vehicular use.
Buro Happold's project leader, David Liaghat, said: "Designing and building a bridge in Rome is any engineer's dream. It embodies fantastic engineering; simplicity, elegance and functionality."
The crossing will provide a link between the sports facilities located on either side of the river as part of a major infrastructure development project which has been planned since 1931.
A city planning department representative, Roberto Morassutt, said of the scheme: "It has an enormous cultural and urban value; the area, set along the town circumference, will become a great public space for cultural events in facilities such as the Auditorium and the new MAXXI gallery."
The bridge is expected to be completed in July 2009.